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Interplay between A-to-I Editing and Splicing of RNA: A Potential Point of Application for Cancer Therapy

Adenosine-to-inosine RNA editing is a system of post-transcriptional modification widely distributed in metazoans which is catalyzed by ADAR enzymes and occurs mostly in double-stranded RNA (dsRNA) before splicing. This type of RNA editing changes the genetic code, as inosine generally pairs with cy...

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Detalles Bibliográficos
Autores principales: Goncharov, Anton O., Shender, Victoria O., Kuznetsova, Ksenia G., Kliuchnikova, Anna A., Moshkovskii, Sergei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105294/
https://www.ncbi.nlm.nih.gov/pubmed/35563631
http://dx.doi.org/10.3390/ijms23095240