Kisspeptin-10 Rescues Cholinergic Differentiated SHSY-5Y Cells from α-Synuclein-Induced Toxicity In Vitro

The neuropathological substrate of dementia with Lewy bodies (DLB) is defined by the inextricable cross-seeding accretion of amyloid-β (Aβ) and α-synuclein (α-syn)-laden deposits in cholinergic neurons. The recent revelation that neuropeptide kisspeptin-10 (KP-10) is able to mitigate Aβ toxicity via...

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Detalles Bibliográficos
Autores principales: Simon, Christopher, Soga, Tomoko, Ahemad, Nafees, Bhuvanendran, Saatheeyavaane, Parhar, Ishwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105316/
https://www.ncbi.nlm.nih.gov/pubmed/35563582
http://dx.doi.org/10.3390/ijms23095193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105316/
https://www.ncbi.nlm.nih.gov/pubmed/35563582
http://dx.doi.org/10.3390/ijms23095193

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