High-throughput characterization of the role of non-B DNA motifs on promoter function

Alternative DNA conformations, termed non-B DNA structures, can affect transcription, but the underlying mechanisms and their functional impact have not been systematically characterized. Here, we used computational genomic analyses coupled with massively parallel reporter assays (MPRAs) to show tha...

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Detalles Bibliográficos
Autores principales: Georgakopoulos-Soares, Ilias, Victorino, Jesus, Parada, Guillermo E., Agarwal, Vikram, Zhao, Jingjing, Wong, Hei Yuen, Umar, Mubarak Ishaq, Elor, Orry, Muhwezi, Allan, An, Joon-Yong, Sanders, Stephan J., Kwok, Chun Kit, Inoue, Fumitaka, Hemberg, Martin, Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105345/
https://www.ncbi.nlm.nih.gov/pubmed/35573091
http://dx.doi.org/10.1016/j.xgen.2022.100111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105345/
https://www.ncbi.nlm.nih.gov/pubmed/35573091
http://dx.doi.org/10.1016/j.xgen.2022.100111

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