Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95

Human serine racemase (hSR) is a pyridoxal-5′-phosphate (PLP)-dependent dimer that catalyzes the formation of D-serine from L-serine, as well as the dehydration of both L- and D-serine to pyruvate and ammonia. As D-serine is a co-agonist of N-methyl-D-aspartate receptors (NMDARs), hSR is a key enzym...

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Detalles Bibliográficos
Autores principales: Giaccari, Roberta, Marchesani, Francesco, Compari, Carlotta, Fisicaro, Emilia, Mozzarelli, Andrea, Campanini, Barbara, Bettati, Stefano, Bruno, Stefano, Faggiano, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105370/
https://www.ncbi.nlm.nih.gov/pubmed/35563349
http://dx.doi.org/10.3390/ijms23094959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105370/
https://www.ncbi.nlm.nih.gov/pubmed/35563349
http://dx.doi.org/10.3390/ijms23094959

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