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Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis

OBJECTIVE: Chronic pancreatitis (CP) is a potentially fatal disease of the exocrine pancreas, with no specific or effective approved therapies. Due to difficulty in accessing pancreas tissues, little is known about local immune responses or pathogenesis in human CP. We sought to characterise pancrea...

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Detalles Bibliográficos
Autores principales: Lee, Bomi, Namkoong, Hong, Yang, Yan, Huang, Huang, Heller, David, Szot, Gregory L, Davis, Mark M, Husain, Sohail Z, Pandol, Stephen J, Bellin, Melena D, Habtezion, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105403/
https://www.ncbi.nlm.nih.gov/pubmed/34702715
http://dx.doi.org/10.1136/gutjnl-2021-324546