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Peripheral Serotonin Deficiency Affects Anxiety-like Behavior and the Molecular Response to an Acute Challenge in Rats

Serotonin is synthetized through the action of tryptophan hydroxylase (TPH) enzymes. While the TPH2 isoform is responsible for the production of serotonin in the brain, TPH1 is expressed in peripheral organs. Interestingly, despite its peripheral localization, alterations of the gene coding for TPH1...

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Detalles Bibliográficos
Autores principales: Sbrini, Giulia, Hanswijk, Sabrina I., Brivio, Paola, Middelman, Anthonieke, Bader, Michael, Fumagalli, Fabio, Alenina, Natalia, Homberg, Judith R., Calabrese, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105435/
https://www.ncbi.nlm.nih.gov/pubmed/35563331
http://dx.doi.org/10.3390/ijms23094941