RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal Differentiation

SIMPLE SUMMARY: Retinoblastoma is a tumor of the eye’s retina, which is the very specialized tissue responsible for vision. In 98% of cases, the tumor is caused by inactivation of the RB1 gene. Due to lack of material and models, the understanding of RB1 mutations in tumor development is still unsat...

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Detalles Bibliográficos
Autores principales: Kanber, Deniz, Woestefeld, Julia, Döpper, Hannah, Bozet, Morgane, Brenzel, Alexandra, Altmüller, Janine, Kilpert, Fabian, Lohmann, Dietmar, Pommerenke, Claudia, Steenpass, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105736/
https://www.ncbi.nlm.nih.gov/pubmed/35565295
http://dx.doi.org/10.3390/cancers14092166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105736/
https://www.ncbi.nlm.nih.gov/pubmed/35565295
http://dx.doi.org/10.3390/cancers14092166

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