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RB1-Negative Retinal Organoids Display Proliferation of Cone Photoreceptors and Loss of Retinal Differentiation
SIMPLE SUMMARY: Retinoblastoma is a tumor of the eye’s retina, which is the very specialized tissue responsible for vision. In 98% of cases, the tumor is caused by inactivation of the RB1 gene. Due to lack of material and models, the understanding of RB1 mutations in tumor development is still unsat...
Autores principales: | Kanber, Deniz, Woestefeld, Julia, Döpper, Hannah, Bozet, Morgane, Brenzel, Alexandra, Altmüller, Janine, Kilpert, Fabian, Lohmann, Dietmar, Pommerenke, Claudia, Steenpass, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105736/ https://www.ncbi.nlm.nih.gov/pubmed/35565295 http://dx.doi.org/10.3390/cancers14092166 |
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