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IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis

Interleukin (IL)-3 is a pleiotropic cytokine that regulates the survival, proliferation, and differentiation of hematopoietic cells. The binding of IL-3 to its receptor activates intracellular signaling, inducing transcription of immediate early genes (IEGs) such as c-fos, c-jun, and c-myc; however,...

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Detalles Bibliográficos
Autores principales: Fujita, Hirotaka, Fujita, Toshitsugu, Fujii, Hodaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105775/
https://www.ncbi.nlm.nih.gov/pubmed/35563758
http://dx.doi.org/10.3390/cells11091451