Molecular Dynamics of DHHC20 Acyltransferase Suggests Principles of Lipid and Protein Substrate Selectivity

Lipid modification of viral proteins with fatty acids of different lengths (S-acylation) is crucial for virus pathogenesis. The reaction is catalyzed by members of the DHHC family and proceeds in two steps: the autoacylation is followed by the acyl chain transfer onto protein substrates. The crystal...

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Detalles Bibliográficos
Autores principales: Panina, Irina, Krylov, Nikolay, Gadalla, Mohamed Rasheed, Aliper, Elena, Kordyukova, Larisa, Veit, Michael, Chugunov, Anton, Efremov, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105814/
https://www.ncbi.nlm.nih.gov/pubmed/35563480
http://dx.doi.org/10.3390/ijms23095091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105814/
https://www.ncbi.nlm.nih.gov/pubmed/35563480
http://dx.doi.org/10.3390/ijms23095091

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