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The Regulatory Roles of Intrinsically Disordered Linker in VRN1-DNA Phase Separation

Biomacromolecules often form condensates to function in cells. VRN1 is a transcriptional repressor that plays a key role in plant vernalization. Containing two DNA-binding domains connected by an intrinsically disordered linker (IDL), VRN1 was shown to undergo liquid-like phase separation with DNA,...

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Detalles Bibliográficos
Autores principales: Huang, Qiaojing, Wang, Yanyan, Liu, Zhirong, Lai, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106000/
https://www.ncbi.nlm.nih.gov/pubmed/35562982
http://dx.doi.org/10.3390/ijms23094594