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Impact of Secretion-Active Osteoblast-Specific Factor 2 in Promoting Progression and Metastasis of Head and Neck Cancer

SIMPLE SUMMARY: Head and neck cancers (HNC) exhibit poor survival due to metastases. Our study identified osteoblast-specific factor 2 (OSF-2) as overexpressed in primary tumors, lymph node metastases, and the tumor microenvironment. High OSF-2 levels correlate with metastatic disease and reduced su...

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Detalles Bibliográficos
Autores principales: Gül, Désirée, Schweitzer, Andrea, Khamis, Aya, Knauer, Shirley K., Ding, Guo-Bin, Freudelsperger, Laura, Karampinis, Ioannis, Strieth, Sebastian, Hagemann, Jan, Stauber, Roland H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106029/
https://www.ncbi.nlm.nih.gov/pubmed/35565465
http://dx.doi.org/10.3390/cancers14092337