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Lack of impact of OCTN1 gene polymorphisms on clinical outcomes of gabapentinoids in Pakistani patients with neuropathic pain

BACKGROUND AND OBJECTIVE: Gabapentinoids are the first-line drugs for neuropathic pain. These drugs are the substrate of organic cation transporter (OCTN1) for renal excretion and absorption across the intestinal epithelium. Gabapentinoids exhibit wide interindividual variability in daily dosage and...

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Detalles Bibliográficos
Autores principales: Shaheen, Abida, Alam, Syed Mahboob, Azam, Fahad, Saleem, Salman Ahmad, Khan, Moosa, Hasan, Syed Saud, Liaquat, Afrose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106170/
https://www.ncbi.nlm.nih.gov/pubmed/35559956
http://dx.doi.org/10.1371/journal.pone.0266559