A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence

Transmitted/founder (T/F) HIV-1 envelope proteins (Envs) from infected individuals that developed neutralization breadth are likely to possess inherent features desirable for vaccine immunogen design. To explore this premise, we conducted an immunization study in rhesus macaques (RM) using T/F Env s...

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Detalles Bibliográficos
Autores principales: Welbourn, Sarah, Chakraborty, Srirupa, Yang, Jie E., Gleinich, Anne S., Gangadhara, Sailaja, Khan, Salar, Ferrebee, Courtney, Yagnik, Bhrugu, Burton, Samantha, Charles, Tysheena, Smith, S. Abigail, Williams, Danielle, Mopuri, Rohini, Upadhyay, Amit A., Thompson, Justin, Price, Matt A., Wang, Shiyu, Qin, Zhaohui, Shen, Xiaoying, Williams, LaTonya D., Eisel, Nathan, Peters, Tiffany, Zhang, Lu, Kilembe, William, Karita, Etienne, Tomaras, Georgia D., Bosinger, Steven E., Amara, Rama R., Azadi, Parastoo, Wright, Elizabeth R., Gnanakaran, Sandrasegaram, Derdeyn, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106183/
https://www.ncbi.nlm.nih.gov/pubmed/35503780
http://dx.doi.org/10.1371/journal.ppat.1010488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106183/
https://www.ncbi.nlm.nih.gov/pubmed/35503780
http://dx.doi.org/10.1371/journal.ppat.1010488

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