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Structure of a TRAPPII-Rab11 activation intermediate reveals GTPase substrate selection mechanisms
Rab1 and Rab11 are essential regulators of the eukaryotic secretory and endocytic recycling pathways. The transport protein particle (TRAPP) complexes activate these guanosine triphosphatases via nucleotide exchange using a shared set of core subunits. The basal specificity of the TRAPP core is towa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106297/ https://www.ncbi.nlm.nih.gov/pubmed/35559680 http://dx.doi.org/10.1126/sciadv.abn7446 |