Cohesin-dependence of neuronal gene expression relates to chromatin loop length

Cohesin and CTCF are major drivers of 3D genome organization, but their role in neurons is still emerging. Here, we show a prominent role for cohesin in the expression of genes that facilitate neuronal maturation and homeostasis. Unexpectedly, we observed two major classes of activity-regulated gene...

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Detalles Bibliográficos
Autores principales: Calderon, Lesly, Weiss, Felix D, Beagan, Jonathan A, Oliveira, Marta S, Georgieva, Radina, Wang, Yi-Fang, Carroll, Thomas S, Dharmalingam, Gopuraja, Gong, Wanfeng, Tossell, Kyoko, de Paola, Vincenzo, Whilding, Chad, Ungless, Mark A, Fisher, Amanda G, Phillips-Cremins, Jennifer E, Merkenschlager, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106336/
https://www.ncbi.nlm.nih.gov/pubmed/35471149
http://dx.doi.org/10.7554/eLife.76539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106336/
https://www.ncbi.nlm.nih.gov/pubmed/35471149
http://dx.doi.org/10.7554/eLife.76539

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