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Benefits of aerobic exercise in myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is a multisystem trinucleotide repeat expansion disorder characterized by the misregulated alternative splicing of critical mRNAs. Previous work in a transgenic mouse model indicated that aerobic exercise effectively improves splicing regulation and function in skelet...

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Detalles Bibliográficos
Autores principales: Mackenzie, Samuel J., Hamel, Johanna, Thornton, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106338/
https://www.ncbi.nlm.nih.gov/pubmed/35575095
http://dx.doi.org/10.1172/JCI160229