microRNA-92a promotes CNS autoimmunity by modulating the regulatory and inflammatory T cell balance

A disequilibrium between immunosuppressive Tregs and inflammatory IL-17–producing Th17 cells is a hallmark of autoimmune diseases, including multiple sclerosis (MS). However, the molecular mechanisms underlying the Treg and Th17 imbalance in CNS autoimmunity remain largely unclear. Identifying the f...

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Detalles Bibliográficos
Autores principales: Fujiwara, Mai, Raheja, Radhika, Garo, Lucien P., Ajay, Amrendra K., Kadowaki-Saga, Ryoko, Karandikar, Sukrut H., Gabriely, Galina, Krishnan, Rajesh, Beynon, Vanessa, Paul, Anu, Patel, Amee, Saxena, Shrishti, Hu, Dan, Healy, Brian C., Chitnis, Tanuja, Gandhi, Roopali, Weiner, Howard L., Murugaiyan, Gopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106347/
https://www.ncbi.nlm.nih.gov/pubmed/35298438
http://dx.doi.org/10.1172/JCI155693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106347/
https://www.ncbi.nlm.nih.gov/pubmed/35298438
http://dx.doi.org/10.1172/JCI155693

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