FOXK2 promotes ovarian cancer stemness by regulating the unfolded protein response pathway

Understanding the regulatory programs enabling cancer stem cells (CSCs) to self-renew and drive tumorigenicity could identify new treatments. Through comparative chromatin-state and gene expression analyses in ovarian CSCs versus non-CSCs, we identified FOXK2 as a highly expressed stemness-specific...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqi, Wang, Yinu, Zhao, Guangyuan, Tanner, Edward J., Adli, Mazhar, Matei, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106354/
https://www.ncbi.nlm.nih.gov/pubmed/35349489
http://dx.doi.org/10.1172/JCI151591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106354/
https://www.ncbi.nlm.nih.gov/pubmed/35349489
http://dx.doi.org/10.1172/JCI151591

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