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FOXK2 promotes ovarian cancer stemness by regulating the unfolded protein response pathway
Understanding the regulatory programs enabling cancer stem cells (CSCs) to self-renew and drive tumorigenicity could identify new treatments. Through comparative chromatin-state and gene expression analyses in ovarian CSCs versus non-CSCs, we identified FOXK2 as a highly expressed stemness-specific...
Autores principales: | Zhang, Yaqi, Wang, Yinu, Zhao, Guangyuan, Tanner, Edward J., Adli, Mazhar, Matei, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106354/ https://www.ncbi.nlm.nih.gov/pubmed/35349489 http://dx.doi.org/10.1172/JCI151591 |
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