Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis

Subendothelial macrophage internalization of modified lipids and foam cell formation are hallmarks of atherosclerosis. Deubiquitinating enzymes (DUBs) are involved in various cellular activities; however, their role in foam cell formation is not fully understood. Here, using a loss-of-function lipid...

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Detalles Bibliográficos
Autores principales: Wang, Biqing, Tang, Xuening, Yao, Liu, Wang, Yuxin, Chen, Zhipeng, Li, Mengqi, Wu, Naishi, Wu, Dawei, Dai, Xiangchen, Jiang, Hongfeng, Ai, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106359/
https://www.ncbi.nlm.nih.gov/pubmed/35389885
http://dx.doi.org/10.1172/JCI154217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106359/
https://www.ncbi.nlm.nih.gov/pubmed/35389885
http://dx.doi.org/10.1172/JCI154217

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