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Starvation mediates pancreatic cancer cell sensitivity to ferroptosis via ERK1/2, JNK and changes in the cell mesenchymal state

Pancreatic cancer is a highly metastatic and therapy-resistant disease. In the present study, the prospects of a novel approach to kill pancreatic cancer cells were examined: Starvation combined with ferroptosis induction. Established pancreatic cancer cell lines (Miapaca2, Panc-1, Su.86.86 and T3M4...

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Detalles Bibliográficos
Autores principales: Zalyte, Egle, Cicenas, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106375/
https://www.ncbi.nlm.nih.gov/pubmed/35514314
http://dx.doi.org/10.3892/ijmm.2022.5140