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The Role of PKM2 in the Regulation of Mitochondrial Function: Focus on Mitochondrial Metabolism, Oxidative Stress, Dynamic, and Apoptosis. PKM2 in Mitochondrial Function

The M2 isoform of pyruvate kinase (PKM2) is one isoform of pyruvate kinase (PK). PKM2 is expressed at high levels during embryonic development and tumor progression and is subject to complex allosteric regulation. PKM2 is a special glycolytic enzyme that regulates the final step of glycolysis; the r...

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Detalles Bibliográficos
Autores principales: Gao, Jing, Zhao, Yuwei, Li, Tao, Gan, Xueqi, Yu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106463/
https://www.ncbi.nlm.nih.gov/pubmed/35571239
http://dx.doi.org/10.1155/2022/7702681