RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m(6)A-YTHDF2-dependent manner

RNA N6-methyladenosine (m(6)A) is an emerging regulator of mRNA modifications and represents a novel player in tumorigenesis. Although it has functional significance in both pathological and physiological processes, the role of m(6)A modification in pancreatic ductal cancer (PDAC) remains elusive. H...

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Detalles Bibliográficos
Autores principales: Tan, Zhen, Shi, Si, Xu, Jin, Liu, Xiaomeng, Lei, Yubin, Zhang, Bo, Hua, Jie, Meng, Qingcai, Wang, Wei, Yu, Xianjun, Liang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106577/
https://www.ncbi.nlm.nih.gov/pubmed/35422475
http://dx.doi.org/10.1038/s41388-022-02306-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106577/
https://www.ncbi.nlm.nih.gov/pubmed/35422475
http://dx.doi.org/10.1038/s41388-022-02306-w

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