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Quadrivalent mosaic HexaPro-bearing nanoparticle vaccine protects against infection of SARS-CoV-2 variants

Emerging SARS-CoV-2 variants of concern (VOCs) harboring multiple mutations in the spike protein raise concerns on effectiveness of current vaccines that rely on the ancestral spike protein. Here, we design a quadrivalent mosaic nanoparticle vaccine displaying spike proteins from the SARS-CoV-2 prot...

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Detalles Bibliográficos
Autores principales: Kang, Yin-Feng, Sun, Cong, Sun, Jing, Xie, Chu, Zhuang, Zhen, Xu, Hui-Qin, Liu, Zheng, Liu, Yi-Hao, Peng, Sui, Yuan, Run-Yu, Zhao, Jin-Cun, Zeng, Mu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106700/
https://www.ncbi.nlm.nih.gov/pubmed/35562337
http://dx.doi.org/10.1038/s41467-022-30222-w