Cryo-EM structure of human glucose transporter GLUT4

GLUT4 is the primary glucose transporter in adipose and skeletal muscle tissues. Its cellular trafficking is regulated by insulin signaling. Failed or reduced plasma membrane localization of GLUT4 is associated with diabetes. Here, we report the cryo-EM structures of human GLUT4 bound to a small mol...

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Detalles Bibliográficos
Autores principales: Yuan, Yafei, Kong, Fang, Xu, Hanwen, Zhu, Angqi, Yan, Nieng, Yan, Chuangye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106701/
https://www.ncbi.nlm.nih.gov/pubmed/35562357
http://dx.doi.org/10.1038/s41467-022-30235-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106701/
https://www.ncbi.nlm.nih.gov/pubmed/35562357
http://dx.doi.org/10.1038/s41467-022-30235-5

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