Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ

Pancreatic intraepithelial neoplasia (PanIN) is a precursor of pancreatic ductal adenocarcinoma (PDAC), which commonly occurs in the general populations with aging. Although most PanIN lesions (PanINs) harbor oncogenic KRAS mutations that initiate pancreatic tumorigenesis; PanINs rarely progress to...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Deguchi, Yasunori, Wei, Daoyan, Liu, Fuyao, Moussalli, Micheline J., Deguchi, Eriko, Li, Donghui, Wang, Huamin, Valentin, Lovie Ann, Colby, Jennifer K., Wang, Jing, Zheng, Xiaofeng, Ying, Haoqiang, Gagea, Mihai, Ji, Baoan, Shi, Jiaqi, Yao, James C., Zuo, Xiangsheng, Shureiqi, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106716/
https://www.ncbi.nlm.nih.gov/pubmed/35562376
http://dx.doi.org/10.1038/s41467-022-30392-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106716/
https://www.ncbi.nlm.nih.gov/pubmed/35562376
http://dx.doi.org/10.1038/s41467-022-30392-7

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