Cargo receptor Surf4 regulates endoplasmic reticulum export of proinsulin in pancreatic β-cells

Insulin is an essential peptide hormone that maintains blood glucose levels. Although the mechanisms underlying insulin exocytosis have been investigated, the mechanism of proinsulin export from the endoplasmic reticulum (ER) remains unclear. Here, we demonstrated that Surf4, a cargo receptor homolo...

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Detalles Bibliográficos
Autores principales: Saegusa, Keiko, Matsunaga, Kohichi, Maeda, Miharu, Saito, Kota, Izumi, Tetsuro, Sato, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106718/
https://www.ncbi.nlm.nih.gov/pubmed/35562580
http://dx.doi.org/10.1038/s42003-022-03417-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106718/
https://www.ncbi.nlm.nih.gov/pubmed/35562580
http://dx.doi.org/10.1038/s42003-022-03417-6

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