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Nuclear oligo hashing improves differential analysis of single-cell RNA-seq
Single-cell RNA sequencing (scRNA-seq) offers a high-resolution molecular view into complex tissues, but suffers from high levels of technical noise which frustrates efforts to compare the gene expression programs of different cell types. “Spike-in” RNA standards help control for technical variation...
Autores principales: | Kim, Hyeon-Jin, Booth, Greg, Saunders, Lauren, Srivatsan, Sanjay, McFaline-Figueroa, José L., Trapnell, Cole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106741/ https://www.ncbi.nlm.nih.gov/pubmed/35562344 http://dx.doi.org/10.1038/s41467-022-30309-4 |
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