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Altered canonical and striatal-frontal resting state functional connectivity in children with pathogenic variants in the Ras/mitogen-activated protein kinase pathway

Mounting evidence supports the role of the Ras/mitogen-activated protein kinase (Ras/MAPK) pathway in neurodevelopmental disorders. Here, the authors used a genetics-first approach to examine how Ras/MAPK pathogenic variants affect the functional organization of the brain and cognitive phenotypes in...

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Detalles Bibliográficos
Autores principales: Bruno, Jennifer L., Shrestha, Sharon B., Reiss, Allan L., Saggar, Manish, Green, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106817/
https://www.ncbi.nlm.nih.gov/pubmed/35087195
http://dx.doi.org/10.1038/s41380-021-01422-5