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A Novel Peripheral Biomarker for Depression and Antidepressant Response

In contrast to healthy controls, the heterotrimeric G protein, Gsalpha (Gsα) is ensconced predominantly in lipid rafts in subjects with major depressive disorder (MDD) resulting in impaired stimulation of adenylyl cyclase. In this small proof-of-concept study, we examined the hypothesis that translo...

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Detalles Bibliográficos
Autores principales: Targum, Steven D., Schappi, Jeffrey, Koutsouris, Athanasia, Bhaumik, Runa, Rapaport, Mark H., Rasgon, Natalie, Rasenick, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106819/
https://www.ncbi.nlm.nih.gov/pubmed/34969978
http://dx.doi.org/10.1038/s41380-021-01399-1