Developmental impact of glutamate transporter overexpression on dopaminergic neuron activity and stereotypic behavior

Obsessive-compulsive disorder (OCD) is a disabling condition that often begins in childhood. Genetic studies in OCD have pointed to SLC1A1, which encodes the neuronal glutamate transporter EAAT3, with evidence suggesting that increased expression contributes to risk. In mice, midbrain Slc1a1 express...

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Detalles Bibliográficos
Autores principales: Chohan, Muhammad O., Kopelman, Jared M., Yueh, Hannah, Fazlali, Zeinab, Greene, Natasha, Harris, Alexander Z., Balsam, Peter D., Leonardo, E. David, Kramer, Edgar R., Veenstra-VanderWeele, Jeremy, Ahmari, Susanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106836/
https://www.ncbi.nlm.nih.gov/pubmed/35058566
http://dx.doi.org/10.1038/s41380-021-01424-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106836/
https://www.ncbi.nlm.nih.gov/pubmed/35058566
http://dx.doi.org/10.1038/s41380-021-01424-3

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