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Developmental impact of glutamate transporter overexpression on dopaminergic neuron activity and stereotypic behavior
Obsessive-compulsive disorder (OCD) is a disabling condition that often begins in childhood. Genetic studies in OCD have pointed to SLC1A1, which encodes the neuronal glutamate transporter EAAT3, with evidence suggesting that increased expression contributes to risk. In mice, midbrain Slc1a1 express...
Autores principales: | Chohan, Muhammad O., Kopelman, Jared M., Yueh, Hannah, Fazlali, Zeinab, Greene, Natasha, Harris, Alexander Z., Balsam, Peter D., Leonardo, E. David, Kramer, Edgar R., Veenstra-VanderWeele, Jeremy, Ahmari, Susanne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106836/ https://www.ncbi.nlm.nih.gov/pubmed/35058566 http://dx.doi.org/10.1038/s41380-021-01424-3 |
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