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Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress

Epigenetic factors modify the effects of environmental factors on biological outcomes. Identification of epigenetic changes that associate with PTSD is therefore a crucial step in deciphering mechanisms of risk and resilience. In this study, our goal is to identify epigenetic signatures associated w...

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Detalles Bibliográficos
Autores principales: Katrinli, Seyma, Maihofer, Adam X., Wani, Agaz, Pfeiffer, John R., Ketema, Elizabeth, Ratanatharathorn, Andrew, Baker, Dewleen G., Boks, Marco P., Geuze, Elbert, Kessler, Ronald C., Risbrough, Victoria B., Rutten, Bart P. F., Stein, Murray B., Ursano, Robert J., Vermetten, Eric, Logue, Mark W., Nievergelt, Caroline M., Smith, Alicia K., Uddin, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106882/
https://www.ncbi.nlm.nih.gov/pubmed/34992238
http://dx.doi.org/10.1038/s41380-021-01398-2