Caspase-11 Interaction with NLRP3 Potentiates the Noncanonical Activation of the NLRP3 Inflammasome

Caspase-11 detection of intracellular lipopolysaccharide (LPS) from invasive Gram-negative bacteria mediates noncanonical activation of the NLRP3 inflammasome. While avirulent bacteria do not invade the cytosol, their presence in tissues necessitates clearance and immune system mobilization. Despite...

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Detalles Bibliográficos
Autores principales: Moretti, Julien, Jia, Baosen, Hutchins, Zachary, Roy, Soumit, Yip, Hilary, Wu, Jiahui, Shan, Meimei, Jaffrey, Samie R., Coers, Jörn, Blander, J. Magarian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106893/
https://www.ncbi.nlm.nih.gov/pubmed/35487985
http://dx.doi.org/10.1038/s41590-022-01192-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106893/
https://www.ncbi.nlm.nih.gov/pubmed/35487985
http://dx.doi.org/10.1038/s41590-022-01192-4

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