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Caspase-11 Interaction with NLRP3 Potentiates the Noncanonical Activation of the NLRP3 Inflammasome

Caspase-11 detection of intracellular lipopolysaccharide (LPS) from invasive Gram-negative bacteria mediates noncanonical activation of the NLRP3 inflammasome. While avirulent bacteria do not invade the cytosol, their presence in tissues necessitates clearance and immune system mobilization. Despite...

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Detalles Bibliográficos
Autores principales:	Moretti, Julien, Jia, Baosen, Hutchins, Zachary, Roy, Soumit, Yip, Hilary, Wu, Jiahui, Shan, Meimei, Jaffrey, Samie R., Coers, Jörn, Blander, J. Magarian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106893/ https://www.ncbi.nlm.nih.gov/pubmed/35487985 http://dx.doi.org/10.1038/s41590-022-01192-4

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