Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signaling

Regulatory T cells (Tregs) require (interleukin-2) IL-2 for their homeostasis by affecting their proliferation, survival, and activation. Here we investigated transcriptional and epigenetic changes after acute, periodic, and persistent IL-2 receptor (IL-2R) signaling in murine peripheral Tregs in vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Moro, Alejandro, Gao, Zhen, Wang, Lily, Yu, Aixin, Hsiung, Sunnie, Ban, Yuguang, Yan, Aimin, Sologon, Corneliu M., Chen, X. Steven, Malek, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106907/
https://www.ncbi.nlm.nih.gov/pubmed/35449416
http://dx.doi.org/10.1038/s41590-022-01179-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106907/
https://www.ncbi.nlm.nih.gov/pubmed/35449416
http://dx.doi.org/10.1038/s41590-022-01179-1

Ejemplares similares