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Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signaling

Regulatory T cells (Tregs) require (interleukin-2) IL-2 for their homeostasis by affecting their proliferation, survival, and activation. Here we investigated transcriptional and epigenetic changes after acute, periodic, and persistent IL-2 receptor (IL-2R) signaling in murine peripheral Tregs in vi...

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Detalles Bibliográficos
Autores principales:	Moro, Alejandro, Gao, Zhen, Wang, Lily, Yu, Aixin, Hsiung, Sunnie, Ban, Yuguang, Yan, Aimin, Sologon, Corneliu M., Chen, X. Steven, Malek, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106907/ https://www.ncbi.nlm.nih.gov/pubmed/35449416 http://dx.doi.org/10.1038/s41590-022-01179-1

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