Calcium-Sensing Receptor Antagonist NPS-2143 Inhibits Breast Cancer cell Proliferation, Migration and Invasion via Downregulation of p-ERK1/2, Bcl-2 and Integrin β1 and Induces Caspase 3/7 Activation

Purpose: Calcium-sensing receptor (CaSR) has been associated with breast cancer metastasis tothe bone. Targeting chemoattractant factors, such as calcium, that are released in response tobone resorption could prevent metastasis and induce apoptosis of cancer cells. In the presentstudy, we investigat...

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Detalles Bibliográficos
Autores principales: Alqudah, Mohammad A.Y., Azaizeh, Marwah, Zayed, Aref, Asaad, Leen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106957/
https://www.ncbi.nlm.nih.gov/pubmed/35620345
http://dx.doi.org/10.34172/apb.2022.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106957/
https://www.ncbi.nlm.nih.gov/pubmed/35620345
http://dx.doi.org/10.34172/apb.2022.037

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