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Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells

Purpose: Apatinib has been utilized in colon cancer therapies but its efficiency and molecularmechanism are not fully understood. Chemotherapy in combination with non-toxic compoundscan be an effective treatment strategy for cancer. Consequently, this study was carried out toevaluate the effects of...

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Detalles Bibliográficos
Autores principales: Mohammadian, Mahshid, Rostamzadeh Khameneh, Zakieh, Emamgholizadeh Minaei, Soraya, Ebrahimifar, Meysam, Esgandari, Kosar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106969/
https://www.ncbi.nlm.nih.gov/pubmed/35620326
http://dx.doi.org/10.34172/apb.2022.040