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Highly potent multivalent VHH antibodies against Chikungunya isolated from an alpaca naïve phage display library

BACKGROUND: Chikungunya virus (CHIKV) is a re-emerged mosquito-borne alphavirus that can cause musculoskeletal diseases, imposing a substantial threat to public health globally. High-affinity antibodies are need for diagnosis and treatment of CHIKV infections. As a potential diagnostic and therapeut...

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Detalles Bibliográficos
Autores principales: Li, Qianlin, Zhang, Fuqiang, Lu, Yi, Hu, Huan, Wang, Jin, Guo, Cheng, Deng, Qiang, Liao, Conghui, Wu, Qin, Hu, Tingsong, Chen, Zeliang, Lu, Jiahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107221/
https://www.ncbi.nlm.nih.gov/pubmed/35568912
http://dx.doi.org/10.1186/s12951-022-01417-6