A bioinformatic analysis of WFDC2 (HE4) expression in high grade serous ovarian cancer reveals tumor-specific changes in metabolic and extracellular matrix gene expression

Human epididymis protein-4 (HE4/WFDC2) has been well-studied as an ovarian cancer clinical biomarker. To improve our understanding of its functional role in high grade serous ovarian cancer, we determined transcriptomic differences between ovarian tumors with high- versus low-WFDC2 mRNA levels in Th...

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Detalles Bibliográficos
Autores principales: James, Nicole E., Gura, Megan, Woodman, Morgan, Freiman, Richard N., Ribeiro, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107348/
https://www.ncbi.nlm.nih.gov/pubmed/35568777
http://dx.doi.org/10.1007/s12032-022-01665-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107348/
https://www.ncbi.nlm.nih.gov/pubmed/35568777
http://dx.doi.org/10.1007/s12032-022-01665-4

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