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ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

Atypical teratoid/rhabdoid tumor (ATRT) is an aggressive central nervous system tumor characterized by loss of SMARCB1/INI1 protein expression and comprises three distinct molecular groups, ATRT–TYR, ATRT–MYC and ATRT–SHH. ATRT–SHH represents the largest molecular group and is heterogeneous with reg...

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Detalles Bibliográficos
Autores principales: Federico, Aniello, Thomas, Christian, Miskiewicz, Katarzyna, Woltering, Niklas, Zin, Francesca, Nemes, Karolina, Bison, Brigitte, Johann, Pascal D., Hawes, Debra, Bens, Susanne, Kordes, Uwe, Albrecht, Steffen, Dohmen, Hildegard, Hauser, Peter, Keyvani, Kathy, van Landeghem, Frank K. H., Lund, Eva Løbner, Scheie, David, Mawrin, Christian, Monoranu, Camelia-Maria, Parm Ulhøi, Benedicte, Pietsch, Torsten, Reinhard, Harald, Riemenschneider, Markus J., Sehested, Astrid, Sumerauer, David, Siebert, Reiner, Paulus, Werner, Frühwald, Michael C., Kool, Marcel, Hasselblatt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107423/
https://www.ncbi.nlm.nih.gov/pubmed/35501487
http://dx.doi.org/10.1007/s00401-022-02424-5