The mitochondrial DNA constitution shaping T-cell immunity in patients with rectal cancer at high risk of metastatic progression

PURPOSE: A significant percentage of colorectal cancer patients proceeds to metastatic disease. We hypothesised that mitochondrial DNA (mtDNA) polymorphisms, generated by the high mtDNA mutation rate of energy-demanding clonal immune cell expansions and assessable in peripheral blood, reflect how ef...

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Detalles Bibliográficos
Autores principales: Bousquet, P. A., Meltzer, S., Fuglestad, A. J., Lüders, T., Esbensen, Y., Juul, H. V., Johansen, C., Lyckander, L. G., Bjørnetrø, T., Inderberg, E. M., Kersten, C., Redalen, K. R., Ree, A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107448/
https://www.ncbi.nlm.nih.gov/pubmed/34961902
http://dx.doi.org/10.1007/s12094-021-02756-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107448/
https://www.ncbi.nlm.nih.gov/pubmed/34961902
http://dx.doi.org/10.1007/s12094-021-02756-w

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