Cargando…

The mitochondrial DNA constitution shaping T-cell immunity in patients with rectal cancer at high risk of metastatic progression

PURPOSE: A significant percentage of colorectal cancer patients proceeds to metastatic disease. We hypothesised that mitochondrial DNA (mtDNA) polymorphisms, generated by the high mtDNA mutation rate of energy-demanding clonal immune cell expansions and assessable in peripheral blood, reflect how ef...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bousquet, P. A., Meltzer, S., Fuglestad, A. J., Lüders, T., Esbensen, Y., Juul, H. V., Johansen, C., Lyckander, L. G., Bjørnetrø, T., Inderberg, E. M., Kersten, C., Redalen, K. R., Ree, A. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107448/ https://www.ncbi.nlm.nih.gov/pubmed/34961902 http://dx.doi.org/10.1007/s12094-021-02756-w

Ejemplares similares

Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Corrigendum to “Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer” [Transl Oncol 12 (8) (2019) 1038–1044]
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Next-generation sequencing reveals mitogenome diversity in plasma extracellular vesicles from colorectal cancer patients
por: Bjørnetrø, Tonje, et al.
Publicado: (2023)

Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Sex disparities in vitamin D status and the impact on systemic inflammation and survival in rectal cancer
por: Abrahamsson, Hanna, et al.
Publicado: (2021)

Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer()()
por: Bousquet, Paula A., et al.
Publicado: (2018)

An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer
por: Bjørnetrø, Tonje, et al.
Publicado: (2019)

The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2021)

Comparison of Intravoxel incoherent motion imaging and multiecho dynamic contrast‐based MRI in rectal cancer
por: Bakke, Kine Mari, et al.
Publicado: (2019)

Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
por: Bains, Simer J., et al.
Publicado: (2019)

High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
por: Abrahamsson, Hanna, et al.
Publicado: (2019)

Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells
por: Risberg, Karianne, et al.
Publicado: (2016)

Imaging the tumour microenvironment in rectal cancer: Decline in tumour blood flow during radiotherapy predicts good outcome
por: Bakke, Kine Mari, et al.
Publicado: (2023)

Energy Metabolism Is Altered in Radioresistant Rectal Cancer
por: Buckley, Croí E., et al.
Publicado: (2023)

Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2016)

Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
por: Kalanxhi, Erta, et al.
Publicado: (2018)

Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
por: Bjørnetrø, Tonje, et al.
Publicado: (2021)

Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer
por: Hektoen, Helga Helseth, et al.
Publicado: (2015)

Semi-automatic tumor segmentation of rectal cancer based on functional magnetic resonance imaging
por: Knuth, Franziska, et al.
Publicado: (2022)

Chemotherapeutic Treatment of Priapism in Metastatic Rectal Cancer
por: Kitai, Y., et al.
Publicado: (2008)

Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening
por: Kalanxhi, Erta, et al.
Publicado: (2016)

Metastatic rectal cancer to the breast
por: Li, Hsiao C, et al.
Publicado: (2009)

Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2022)

Predicting Sasang Constitution Using Body-Shape Information
por: Jang, Eunsu, et al.
Publicado: (2012)

Tumor Phosphatidylinositol-3-Kinase Signaling and Development of Metastatic Disease in Locally Advanced Rectal Cancer
por: Ree, Anne Hansen, et al.
Publicado: (2012)

Influence of marital status on survival from colon and rectal cancer in Denmark
por: Johansen, C, et al.
Publicado: (1996)

Commentary: The Alleged Coupling-Constitution Fallacy and the Mature Sciences
por: Kersten, Luke
Publicado: (2016)

Rectal Invasion by Metastatic Prostate Adenocarcinoma
por: Wadehra, Anshu, et al.
Publicado: (2021)

A Constitutive Description for Shape Memory Alloys with the Growth of Martensite Band
por: Li, Weiguo, et al.
Publicado: (2014)

A Constitutional Mismatch Repair Deficiency Syndrome Presented With an Advanced Rectal Cancer in a Juvenile Female: A Case Report and Literature Review
por: AlAli, Mohammed N, et al.
Publicado: (2022)

Capture and transport of rod-shaped cargo via programmable active particles
por: Stengele, Philipp, et al.
Publicado: (2023)

Analysis of One-Dimensional Ivshin–Pence Shape Memory Alloy Constitutive Model for Sensitivity and Uncertainty
por: Islam, A B M Rezaul, et al.
Publicado: (2020)

Necrotizing fasciitis secondary to bevacizumab treatment for metastatic rectal adenocarcinoma
por: Şendur, Mehmet A. N., et al.
Publicado: (2014)

Measurements of CFTR-Mediated Cl(−) Secretion in Human Rectal Biopsies Constitute a Robust Biomarker for Cystic Fibrosis Diagnosis and Prognosis
por: Sousa, Marisa, et al.
Publicado: (2012)

Case report of diffusely metastatic rectal GIST
por: Puckett, Yana, et al.
Publicado: (2017)

Cutaneous Metastatic Rectal Adenocarcinoma in Zosteriform Distribution
por: Kwon, In Hyuk, et al.
Publicado: (2016)

Tertiary syphilis mimicking metastatic rectal cancer
por: Smith, Matthew J, et al.
Publicado: (2022)

Constitutive Overexpression of Muscarinic Receptors Leads to Vagal Hyperreactivity
por: Livolsi, Angelo, et al.
Publicado: (2010)

Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis
por: Houben, Roland, et al.
Publicado: (2004)

Metastatic rectal cancer in the ampulla of Vater: A unique case
por: Samara, Athina A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7p7veu87639kn8nfcsh3l71sh7