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Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43
Intracellular accumulation of abnormal proteins with conformational changes is the defining neuropathological feature of neurodegenerative diseases. The pathogenic proteins that accumulate in patients' brains adopt an amyloid-like fibrous structure and exhibit various ultrastructural features....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107452/ https://www.ncbi.nlm.nih.gov/pubmed/35513543 http://dx.doi.org/10.1007/s00401-022-02426-3 |