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Evaluation of the α-casein (CSN1S1) locus as a potential target for a site-specific transgene integration

Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from the α-casein (Csn1s1), β-casein (Csn2), whey acidic protei...

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Detalles Bibliográficos
Autores principales: Smirnov, A. V., Kontsevaya, G. V., Shnaider, T. A., Yunusova, A. M., Feofanova, N. A., Gerlinskaya, L. A., Serova, I. A., Serov, O. L., Battulin, N. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107462/
https://www.ncbi.nlm.nih.gov/pubmed/35568783
http://dx.doi.org/10.1038/s41598-022-12071-1