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Evaluation of the α-casein (CSN1S1) locus as a potential target for a site-specific transgene integration
Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from the α-casein (Csn1s1), β-casein (Csn2), whey acidic protei...
Autores principales: | Smirnov, A. V., Kontsevaya, G. V., Shnaider, T. A., Yunusova, A. M., Feofanova, N. A., Gerlinskaya, L. A., Serova, I. A., Serov, O. L., Battulin, N. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107462/ https://www.ncbi.nlm.nih.gov/pubmed/35568783 http://dx.doi.org/10.1038/s41598-022-12071-1 |
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