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Adiponectin receptors sustain hematopoietic stem cells throughout adulthood by protecting them from inflammation

How are hematopoietic stem cells (HSCs) protected from inflammation, which increases with age and can deplete HSCs? Adiponectin, an anti-inflammatory factor that is not required for HSC function or hematopoiesis, promotes stem/progenitor cell proliferation after bacterial infection and myeloablation...

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Detalles Bibliográficos
Autores principales: Meacham, Corbin E., Jeffery, Elise C., Burgess, Rebecca J., Sivakumar, Charukesi D., Arora, Madison A., Stanley, Anne Marie, Hildinger, Emily M., Crane, Genevieve M., Zhao, Zhiyu, Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107511/
https://www.ncbi.nlm.nih.gov/pubmed/35513711
http://dx.doi.org/10.1038/s41556-022-00909-9