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Adiponectin receptors sustain hematopoietic stem cells throughout adulthood by protecting them from inflammation
How are hematopoietic stem cells (HSCs) protected from inflammation, which increases with age and can deplete HSCs? Adiponectin, an anti-inflammatory factor that is not required for HSC function or hematopoiesis, promotes stem/progenitor cell proliferation after bacterial infection and myeloablation...
Autores principales: | Meacham, Corbin E., Jeffery, Elise C., Burgess, Rebecca J., Sivakumar, Charukesi D., Arora, Madison A., Stanley, Anne Marie, Hildinger, Emily M., Crane, Genevieve M., Zhao, Zhiyu, Morrison, Sean J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107511/ https://www.ncbi.nlm.nih.gov/pubmed/35513711 http://dx.doi.org/10.1038/s41556-022-00909-9 |
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